publications

2020

Castro R, Taetzsch T, Vaughan SK, Godbe K, Chappell J, Settlage RE,Valdez G (2020) Specific labeling of synaptic schwann cells reveals unique cellular and molecular features. eLife

2019

2018

Taetzsch T, Valdez G. (2018) NMJ maintenance and repair in aging.Curr Opin Physiol

Vaughan SK, Sutherland NM, Zhang S, Hatzipetros T, Vieira F, Valdez G. (2018) The ALS-inducing factors, TDP43A315T and SOD1G93A, directly affect and sensitize sensory neurons to stress. Sci. Report

Taetzsch T, Brayman VL, Valdez G. (2018) FGF binding proteins (FGFBPs): Modulators of FGF signaling in the developing, adult, and stressed nervous system. Biochim Biophys Acta Mol Basis

Maxwell N, Castro RW, Sutherland NM, Vaughan KL, Szarowicz MD, de Cabo R, Mattison JA, Valdez G. (2018) α-Motor neurons are spared from aging while their synaptic inputs degenerate in monkeys and mice. Aging Cell

2017

Stockinger J, Maxwell N, Shapiro D, deCabo R, Valdez G. (2017) Caloric Restriction Mimetics Slow Aging of Neuromuscular Synapses and Muscle Fibers. J Gerontol A Biol Sci Med Sci. 

Vaughan SK, Stanley OL, Valdez G. (2017)  Impact of Aging on Proprioceptive Sensory Neurons and Intrafusal Muscle Fibers in Mice. J Gerontol A Biol Sci Med Sci.

2016

Taetzsch T, Tenga M, Valdez G. (2016). Muscle Fibers Secrete FGFBP1 to Slow Degeneration of Neuromuscular Synapses During Aging and Progression of ALS. Journal of Neuroscience.

Dalkin W, Taetzsch T, Valdez G. (2016). The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions. Journal of Visualized Experiments (JoVE).

2015

Vaughan SK, Kemp Z, Hatzipetros T, Vieira F, Valdez G. (2015). Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations.Journal of Comparative Neurology 523(17): 2477-94.

2014

Dittmar WJ, McIver L, Michalak P, Garner HR, Valdez G. (2014). EvoCor: a platform for predicting functionally related genes using phylogenetic and expression profiles. Nucleic Acid Research.

Valdez G, Hayer MP, Feng G, Sanes JR. (2014). The role of muscle microRNAs in repairing the neuromuscular junction. PLOS ONE.

2012

Samuel MA, Valdez G, Tapia JC, Lichtman JW, Sanes JR. (2012). Agrin and synaptic laminin are required to maintain adult neuromuscular junctions. PLoS One 7(10): e46663.

Valdez G, Tapia JC, Lichtman JW, Fox MA, Sanes JR. (2012). Shared resistance to aging and ALS in neuromuscular junctions of specific muscles. PLoS One 7(4): e34640.

2010

Philippidou P, Valdez G, Akmentin W, Bowers WJ, Federoff HJ, Halegoua S. (2010). Trk retrograde signaling requires persistent, Pincher-directed endosomes. Proceedings of the National Academy of Science.

Carlson SS, Valdez G, Sanes JR. (2010). Presynaptic calcium channels and alpha3- integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components.Journal of Neurochemistry.

Valdez G, Tapia JC, Kang H, Clemenson GD Jr, Gage FH, Lichtman JW, Sanes JR. (2010). Attenuation of age related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci USA 107: 14863–68.

2009

Williams AH*, Valdez G*, Moresi V, Qi X, McAnally J, Elliott JL, Bassel-Duby R, Sanes JR, Olson E. (2009). MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science 326: 1549–54.

Proszynski TJ, Gingras J, Valdez G, Krzewski K, Sanes JR. (2009). Podosomes are present in a postsynaptic apparatus and participate in its maturation. Proceedings of the National Academy of Science 106: 18373-8.

2008

Bonanomi D, Fornasiero EF, Valdez G, Halegoua S, Benfenati F, Menegon A, Valtorta F. (2008). Identification of a developmentally-regulated pathway of membrane retrieval in neuronal growth cones. Journal of Cell Science 121: 3757-69.

Nishimune H, Valdez G, Miner JH, Sanes JR. (2008). Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction. J Cell Biol 182: 1201-15.